Phytochemical Investigation of Tradescantia Albiflora and Anti-Inflammatory Butenolide Derivatives

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Chalcone (1,3-diarylprop-2-en-1-one) derivatives have been introduced as selective cyclooxygenase-2 inhibitors. In the present study, anti-nociceptive and anti-inflammatory effects of eight novel compounds were evaluated in male mice and Wistar rats by using the writhing and formalin-induced paw edema tests respectively. The activities of the compounds were compared with celecoxib as a referenc...

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ژورنال

عنوان ژورنال: Molecules

سال: 2019

ISSN: 1420-3049

DOI: 10.3390/molecules24183336